Your 23andMe scan includes genetic analysis on all of the following diseases, traits, and conditions. This list grows every month as new research is published.
Clinical Reports (23)
Clinical Reports give you information about conditions and traits for which there are genetic associations supported by multiple, large, peer-reviewed studies. Those associations must also have a substantial influence on a person's chances of developing the disease or having the trait. Because these associations are widely regarded as reliable, we use them to develop quantitative estimates and definitive explanations of what they mean for you.
Research Reports (72)
Research Reports give you information from research that has not yet gained enough scientific consensus to be included in our Clinical Reports. This research is generally based on high-quality but limited scientific evidence. Because these results have not yet been demonstrated through large, replicated studies, we do not perform complete quantitative analyses of their effects. We do, however, explain how they may–if confirmed–affect your odds of having or developing a trait, condition or disease.
Research Reports also includes scientifically accepted, established research that does not have a dramatic influence on a person's risk for a disease.
- Alcohol Dependence
- Aneurysm
- Ankylosing Spondylitis
- Antidepressant Response
- Asthma
- Atrial Fibrillation
- Attention-Deficit Hyperactivity Disorder
- Avoidance of Errors
- Back Pain
- Baldness
- Beta-Blocker Response
- Bipolar Disorder
- Birth Weight
- Bladder Cancer
- Blood Glucose
- Breast Cancer
- Breast Cancer
- C-reactive Protein Level
- Caffeine Metabolism
- Celiac Disease
- Chronic Lymphocytic Leukemia
- Cluster Headaches
- Colorectal Cancer
- Creutzfeldt-Jakob Disease
- Developmental Dyslexia
- Endometriosis
- Esophageal Cancer
- Eye Color
- Food Preference
- Freckling
- Gallstones
- Glaucoma
- Gout
- HDL Cholesterol Level
- HIV Progression
- Hair Color
- Heart Attack
- Height
- Heroin Addiction
- High Blood Pressure (Hypertension)
- Kidney Disease
- Larynx Cancer
- Longevity
- Lou Gehrig's Disease (ALS)
- Lung Cancer
- Lupus (Systemic Lupus Erythematosus)
- Male Infertility
- Measures of Intelligence
- Memory
- Multiple Sclerosis
- Neuroblastoma
- Nicotine Dependence
- Obesity
- Obesity
- Obsessive-Compulsive Disorder
- Odor Detection
- Oral and Throat Cancer
- Osteoarthritis
- Pain Sensitivity
- Peripheral Arterial Disease
- Persistent Fetal Hemoglobin
- Placental Abruption
- Pre-eclampsia
- Progressive Supranuclear Palsy
- Restless Legs Syndrome
- Schizophrenia
- Sjögren's Syndrome
- Skin Cancer
- Stomach Cancer
- Tardive Dyskinesia
- Tourette's Syndrome
- Uterine Fibroids
How accurate is the genetic data you provide?
23andMe analyzes your DNA using a genotyping chip. The chip we use is an Illumina HumanHap550+ Genotyping BeadChip. 23andMe has also added a customized set of SNPs to the chip.
The accuracy of the chip can be measured in two ways:
First, the HumanHap 550 chip has, on average, a 99% call rate. That means that we receive usable data for, on average, 99% of the SNPs on the HumanHap 550 chip. The remaining 1% of SNPs that do not meet our confidence-based performance standards are labeled "No Call." Unfortunately, it is not possible to guarantee data for every SNP without making the chip many times more expensive.
Second, the reproducibility of the chip is over 99.9%. This means that if we ran the same DNA a second time on a new chip, more than 99.9% of the data would be the same compared to data from the first run.
These performance measures are guaranteed by Illumina for the off-the-shelf HumanHap550 Genotyping BeadChip. Based on previous experience, we expect to exceed this performance. More technical information on the performance of the chip can be found on the manufacturer's website.
Based on internal data, the custom chip has a reproducibility of ~99.6% and a call rate of ~99.9% for the SNPs reported in Health and Traits.
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